Technological Advances of Permanent Seed Brachytherapy
Stephen W. Doggett MD
14642 Newport Ave #470
Tustin California, USA 92780
714 573 9500 Fax 714 573 9505
www.nocancer.com


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Table of Contents

Epidemiology Overview
Brachytherapy Overview
Intraoperative Treatment Planning
Dynamic Dosimetry
Prostascint/MRI Fusion
Nerve Sparing Brachytherapy

 

Prostate Cancer U.S. 2003

#2 cause of male cancer death
220,900 new cases per year
28,900 deaths per year
75% gland confined at diagnosis without evidence of spread

 

Watchful Waiting; Is It Logical or Suicidal?

"Population based studies in Sweden and Denmark have shown that 62% and 63%, respectively, of patients diagnosed with localized prostate cancer will die from the disease if not treated immediately."
Labrie F. Prostate 2000 May 15;43(3):215-22(Laval U)

"In the watchful waiting group there was a 52% likelihood of treatment initiation within 5 years of the diagnosis."
Koppie T et al. J Urol 2000 Jul;164(1):81-8 (UCSF)

 

A Chance to Screen is a Chance to Cure

USA: "Clinically, the case for screening has become stronger, and declining prostate cancer mortality rates may be due in part to early detection and treatment."
Small EJ Curr Opin Oncol 2000 May;12(3):265-72

United Kingdom: "The lack of any improvement in survival rates in cases diagnosed after 1985 (in the UK) is of concern, and suggests that the current management of prostate cancer in both primary and secondary care may need to be reviewed." Majeed A Brit J Urol Int 2000 Jun;85(9):1058-62

Epidemiology 2004 Summary

Prostate cancer death rate is decreasing ; screening and therapy are likely causes.
Watchful waiting is associated with a high death rate and a high rate of subsequent therapy.
Patient/Physician interest in less morbid curative therapies such as seed therapy is accelerating.
Most clinicians believe that screening is effective


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